The rise of herpes – when an infection resists the other

"Every cloud has a silver lining" – this is what people sometimes say. But at that time they do not think of HSV. HSV or Herpes Simplex virus may be uncomfortable, but viruses that stop and other related diseases may occur. At least mice provide bacterial resistance to diseases such as bubble plague. Herpes is only one of the group of viruses called herpes virus, one of the itchy, blistering infections. Eight members of the virus group infect people and lead to many diseases including chickenpox, shingles, myringeal, and actually herpes.

But the virus group remains permanently in the body; Not just for the holidays. Once the immune system protects the primary infection, the virus enters an inactive phase called "latency". It remains hidden and has no visible symptoms. But it is likely to reactivate at any time. Thus, herpesviruses are like lifelong parasites that ensure their own survival and can damage their health status. In extreme cases, latent viruses may cause chronic inflammation, which may cause autoimmune diseases or some cancerous forms.

But herpes has a clear side. The Faculty of Medicine of the University of Washington, Erik Barton and his colleagues discovered that once infected mice entered the latent phase and were shockingly resistant to certain types of bacteria. They are different from their susceptible and uninfected companions, yet they are able to overcome the deadly plague, Yersinia pestis. In mice at least latent herpes viruses pay instead of tenants instead of freeloader substitutes – resistance of bacteria their rent. The latent phase is vital to resistance and Barton discovered that a mutant herpes virus is infected, but does not offer anything to his master.

Viruses function as abnormalities of the immune system. The effect is like raising a terrorist attack, which has increased the level of security where your organization is ready to prevent threats. Viruses activate the release of cytokines at high levels. Cytokines are an immune system chemical. These molecules – IFN-g (interferon-gamma) and TNF-a (tumor necrosis factor) – help to coordinate the control of infections

These chemicals induce macrophages – a white blood cell. These cellular killers consume and digest invasive bacteria. They are actively activated in mice infected with herpes viruses in the latent stage. This is how the immune system protects us against various bacterial invaders. However, in Barton's study, protection was initiated by viruses and maintained for longer than usual. Good for mice.

What do we get from these viruses? Will it have the same effect on us as mice? Barton says so. In his research, two different strains – gHV68 (mouse genetic herpes 68) and MCMV (mouse cytomegalovirus) – had similar effects. He thinks bacterial resistance is a universal feature of herpes viruses.

Source by Louis V Lim

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